A care management program coordinates the delivery of healthcare, aims to improve patient outcomes, and focuses on optimizing the utilization of care. Although these programs can be effective, they can also involve significant investments of time, money, and resources. For this reason, it is important to regularly monitor and evaluate the effectiveness of these programs as well as the return on investment (ROI). There are many methods available to evaluate a care management program and determine an appropriate ROI. Wakely and RecoveryOne have partnered to provide an overview of care management program analyses available and address how these methodologies and principles can be applied specifically to a MSK care management program.